KMID : 1007320150210010053
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Journal of the Korean Society of Menopause 2015 Volume.21 No. 1 p.53 ~ p.59
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Postmenopausal Meigs¡¯ Syndrome in Elevated CA-125: A Case Report
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Park Jung-Woo
Bae Jong-Woon
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Abstract
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Meigs¡¯ syndrome is a benign ovarian tumor associated with ascites and pleural effusion. Elevated cancer antigen 125 (CA-125) in Meigs¡¯ syndrome is an unusual clinical condition reported in few cases. We report here on a 61-year-old woman who presented with dyspnea; in imaging assessment, a heterogeneous pelvic mass measuring 12 ¡¿ 11 cm with ascitic fluid was reported. Pleural effusion was detected on Chest X-ray. Aspiration of pleural fluid showed no evidence of malignancy. CA-125 level was 347 IU/mL. The patient underwent laparotomy during which a mass measuring 12 ¡¿ 11 cm was detected in her left adnexa. Histology showed ovarian thecoma. The mass was resected, and, after that, the symptoms disappeared and CA-125 level reached 19 IU/mL. The patient had experienced no problem after 12 months of follow up. Although postmenopausal women with ovarian tumor, ascites, pleural effusion, and elevation of CA-125 levels probably have malignant ovarian tumors, Meigs¡¯ syndrome must be considered in the differential diagnosis.
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KEYWORD
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CA-125, Meigs syndrome, Pleural effusion
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